Podcasts

How the STEP-UP trial came to life,  and what made the 7.2mg dose possible

What the data actually says about...

Takeaways

• The study examines the overlap between clinical and anthropometric obesity.
• Anthropometric measures include waist circumference, waist-to-hip ratio, and...

Learn what age-related macular degeneration (AMD) is

What causes AMD

The types of AMD

The update on NAION – listen...

• Menopausal hormonal therapy should not be a blanket recommendation for everyone going through menopause
• Weight management in women is...

• Dr. Grant Tinsley joins the discussion as the body composition expert.
• Myostatin is a key regulator of muscle growth.
...

Takeaways:

• The MAHA report aims to address public health issues but lacks actionable policies.
• Historical context is crucial for...

Click to read Joy Prescriptions

Drs. Karl and Spencer talk to Dr. Tiffany Moon all about Joy Prescriptions....

• Tirzepatide is more effective for weight loss than semaglutide.
• Cost-effectiveness is crucial in prescribing weight loss medications.
• Patients with...

Takeaways

• MASH is a significant obesity-related complication.
• Semaglutide shows promise in treating MASH.
• Weight loss is crucial for improving...

Drs. Karl and Spencer chat with return guest Dr. Lauren Semple about creatine, protein, cortisol, fasting exercise, and training in...

Drs. Karl and Spencer discuss a new study looking at tirzepatide and metabolic rate. They also discuss a patient case...

Drs. Karl and Spencer discuss the claim that GLP-1 meds cause more fat cells.

Learn about if and how GLP-1...

Drs. Karl and Spencer talk to Dr. Kenneth Qiu all about direct medical care – the future of medicine.

Learn...

Drs. Karl and Spencer discuss with Dr. Grant Tinsley all about the new analysis of how much "lean mass" is...

Drs. Karl and Spencer discuss how bad the Hims and Hers ad was.

From an outside perspective, the ad may...

Drs. Karl and Spencer chat with NMN and NAD expert Dr. Charles Brenner all about these supposed longevity supplements.

Learn...

Drs. Karl and Spencer chat with Dr. Fatima Cody Stanford all about obesity, genetics, and her appearance on 60 minutes.

Drs. Karl and Spencer chat about the new Lancet Commission's report on Clinical Obesity along with the new study on...

Drs. Karl and Spencer chat with Dr. Sowa about her book The Ozempic Revolution.

Learn:

Why she wrote the book.

Drs. Karl and Spencer discuss the concept of "microdosing" GLP-1 receptor agonists along with talk about the new top line...

Drs. Karl and Spencer chat with Dr. Lauren Colenso-Semple all about how the menstrual cycle and how it should affect...

Drs. Karl and Spencer discuss the topline results from Surmount 5 which put Zepbound (tirzepatide) against Wegovy (semaglutide) for weight...

Drs. Karl and Spencer chat with Dr. Shivani Misra, a metabolic specialist physician researcher from the UK, all about the...

Drs. Karl and Spencer chat with AtlasMD – Dr. Josh Umbehr all about making healthcare cheaper using direct primary care.